Review Questions

1. What are three examples of behaviors that can help prevent cancer?


2. What are six hallmarks of cancer?


3. What general molecular defect leads to all forms of cancer?


4. What are 2 general ways in which a person can come to have genes that are damaged?


5. What are some examples of cancer susceptibility genes?


6. True or False: All breast tumors have the same complement of active and inactive genes.


7. Give an example of a cancer that acquires self-sufficiency in growth factor signaling by increasing the production of a growth factor.


8. True or False: Integrin-dependent cell adhesion is required in order for growth factor signaling to occur properly.


9. Integrin receptors span the plasma membrane to link what two structural components inside and outside of the cell?


10. What is the term for integrin-rich sites of cell-substratum attachment?