Facilitator Questions

1. What is metabolic labeling?
   
   
2. What is a “fluorogenic”, or smart probe? Why are smart probes desirable? What are the three components necessary to make a smart fluorogenic probe for use in the bioorthogonal chemical reporter approach?
   
   
3. What is a control experiment? Why is a control experiment necessary?
   
   
4. Why is the development of technology to optically image glycans important in the understanding of human disease? How might you imagine this technology to be used clinically?